| 摘要: |
| 目的:探讨妊娠中期口服75 g葡萄糖耐量(OGTT)正常的孕妇妊娠晚期体质量增长过快对妊娠期并发症及围生期结局的影响。方法:随机选择2015年10月至2016年9月在天津医科大学第二医院产科产检并分娩,妊娠前体质量指数(BMI)、妊娠24~27+6周75 g OGTT结果均正常的孕妇422例为研究对象,至28~36周时,体质量增长≥4000 g(体质量增速≥500 g/w)的病例为研究组(103例),<4000 g(体质量增速<500 g/w)的为对照组(319例),采用成组t检验或χ~2检验比较两组孕产妇的妊娠期并发症发生率及围生期结局。结果:研究组GDM(7.8%)、妊娠期高血压(6.8%)、轻度子痫前期(4.9%)、胎膜早破(12.6%)、羊水过多(4.9%)等妊娠期并发症的发生率明显高于对照组(2.8%、2.5%、1.9%、7.2%、1.3%),差异有统计学意义(P<0.01);妊娠36周复查OGTT,研究组服糖后2小时血糖、Hb A1c明显高于对照组(P<0.01);研究组巨大儿发生率(10.7%)、新生儿出生体质量3677±351 g、新生儿低血糖发生率(4.9%)、剖宫产率(39.8%)均明显高于对照组(6.0%、3328±367 g、2.5%、34.2%),差异有统计学意义(P<0.01),两组新生儿阿氏评分差异无统计学意义(P>0.05)。结论:妊娠中期OGTT正常的孕妇,如果饮食管理不良,体质量增长过快可能会增加妊娠晚期的并发症的发生率和围生期不良结局。 |
| 关键词: 妊娠晚期 体质量增长 妊娠期糖尿病 妊娠期并发症 围生期结局 |
| DOI： |
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| 基金项目: |
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| Analysis of Perinatal Outcomes and Pregnancy Complications at the Third Trimester in Excessive Fast Weight Gain Pregnant Women Who Had Normal 75g OGTT at the Second Trimester |
| DONG Wei;CHEN Lihong;YIN Lirong |
| (The Second Hospital of Tianjin Medical University) |
| Abstract: |
| Objective:To analysis perinatal outcome and pregnancy complications in the third trimester in excessive fast weight gain pregnant women who had normal 75 g oral glucose tolerance test(OGTT) at the second trimester.Methods:422 pregnant women who examined and delivered in Department of Obstetrics,the Second Hospital of Tianjin Medical University from October 2015 to September 2016 were selected randomly for this study.All of them had normal pre-pregnancy body mass index(BMI) and 75 g OGTT test at 24-27+6 gestational weeks.Mass growth more than 4000 g from 28-36 gestational weeks(average mass growth rate≥500 g/w) were enrolled in study group(n = 103),while others were included in control group(n = 319).Statistical analysis was performed by t test and χ~2 test.Results:The incidence rate of Gestational diabetes mellitus(GDM)(7.8%),gestational hypertensive(6.8%),mild preeclampsia(4.9%),premature rupture of membranes(PROM)(12.6%) and polyhydramnios(4.9%) in study group was significant higher than those in control group(2.8%,2.5%,1.9%,7.2%,1.3%).The rate of cesarean section(39.8%),macrosomia(10.7%),and neonatal hypoglycemia(4.9%) in study group was significant higher than those in control group(34.2%,6.0%,2.5%).The average birth weight in the study group was significant higher than that in the control group(3677±351 g vs 3328±367 g,P<0.01).There was no significant difference in Apgar score between two groups(P > 0.05).Conclusions:In the second trimester 75 g OGTT test normal pregnant women,poor diet and exercise management and excessive fast weight gain may increase the incidence of pregnancy complications and poorer perinatal outcomes. |
| Key words: Thirdtrimester Bodyqualitygrowth Gestationaldiabetesmellitus Pregnancycomplications Perinataloutcome |
