| 摘要: |
| 目的:探讨妊娠中晚期正常胎儿肺体积、肺质量-体质量比(FLB)正常参考值范围及胎肺体积随孕周和胎儿体质量的变化关系。方法:选取妊娠18~39+6周的正常胎儿198例,应用三维超声VOCAL旋转技术测量胎儿左肺体积、右肺体积及肺总体积,应用二维超声测量的胎儿生物参数,经Hadlock方程系统获得胎儿体质量,计算FLB值,计算胎肺体积及FLB的正常参考值范围,应用Pearson相关分析来分析胎儿肺体积与孕周和胎儿体质量的关系。结果:胎儿左肺、右肺及总肺体积三维VOCAL技术测值随孕周和胎儿体质量的增加呈上升趋势。左肺、右肺及总肺体积与孕周呈高度正相关(左肺体积:r=0.970,P<0.001;右肺体积:r=0.972,P<0.001;总肺体积:r=0.970,P<0.001);左肺、右肺及总肺体积与体质量也呈高度正相关(左肺体积:r=0.978,P<0.001;右肺体积:r=0.984,P<0.001;总肺体积:r=0.979,P<0.001)。FLB值不随孕周变化,正常值范围约0.026~0.032。结论:妊娠中晚期正常胎儿的肺体积随妊娠周数及胎儿体质量的增加而增大,胎肺体积及FLB参考值范围可对评估胎肺发育提供重要理论依据。 |
| 关键词: 超声检查 三维 肺体积 胎儿发育 |
| DOI： |
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| 基金项目:宁夏医科大学科学研究基金资助项目(编号:XM2015056) |
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| Assessment of Normal Fetal Lung Development Using Three-Dimensional Ultrasound VOCAL Rotation Technology |
| DING Lili;LIU Yanxiang;JI Xueqin |
| (General Hospital of Ningxia Medical University) |
| Abstract: |
| Objective:To explore the normal reference value range of normal fetal lung volume and lung weight to body weight ratio( FLB) in the second trimester and third trimester,and to evaluate the correlation between fetal lung volumes and gestational age. Methods:198 gestational age 18 ~ 39+6 weeks fetal left and right lung volumes were measured by three-dimensional ultrasound VOCAL rotation technology.Fetal weight was assessed by two-dimensional ultrasound and Hadlock equation system.FLB were calculated.The normal reference value range of normal fetal lung volume and FLB were calculated.The correlation between fetal lung volumes and gestational age was assessed by Pearson correlation analysis.Results:The volumes of left lung,right lung and total lung increased with the increase of gestational age and body weight. The volumes of left lung,right lung and total lung were highly correlated with gestational age and fetal weight( The left lung volume,r = 0. 970,P <0. 001. The right lung volume,r = 0. 972,P<0. 001.The total lung volume,r = 0. 970,P<0. 001.),and the correlation coefficient was 0.970,0. 972,0. 970,0. 978,0. 984,0. 979. The FLB did not change with gestational age,and the normal range was about 0. 026-0. 032.Conclusions:The fetal lung volumes increase with the increase of gestational age and fetal weight in second trimester and third trimester.The normal reference range of fetal lung volume and FLB can provide important theoretical basis for evaluation of fetal lung development. |
| Key words: Ultrasonography Three-dimensional Lungvolume Fetaldevelopment |
